CFZ 533

Drug Profile

CFZ 533

Alternative Names: CFZ533; OM11-62-MF

Latest Information Update: 27 Jul 2018

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At a glance

  • Originator Novartis
  • Class Antirheumatics; Monoclonal antibodies
  • Mechanism of Action CD40 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Graves' disease; Lupus nephritis; Myasthenia gravis; Renal transplant rejection; Sjogren's syndrome
  • Phase I Rheumatoid arthritis

Most Recent Events

  • 20 Jul 2018 Phase-II clinical trials in Lupus nephritis in Germany (IV) (EudraCT2017-003230-93)
  • 09 Jul 2018 Phase-II clinical trials in Renal transplant rejection in Sweden (SC, IV) (EudraCT2017-003607-22)
  • 09 May 2018 Phase-II clinical trials in Lupus nephritis in Hungary (IV) (EudraCT2017-003230-93)
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