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4-Hydroxytestosterone transdermal - Curadis

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Drug Profile

4-Hydroxytestosterone transdermal - Curadis

Alternative Names: 4-hydroxy-testosterone; 4-OH-testosterone; 4-OHT - Curadis; CR 1447

Latest Information Update: 05 Jul 2023

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At a glance

  • Originator Curadis
  • Developer Curadis; Swiss Group for Clinical Cancer Research
  • Class Anabolic steroids; Antineoplastics; Small molecules; Steroids; Testosterone congeners
  • Mechanism of Action Androgen receptor agonists; Estrogen receptor alpha modulators; Estrogen receptor beta modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Breast cancer

Most Recent Events

  • 27 Jun 2023 MEI Pharma terminates phase II trials in Breast cancer (Late-stage disease, Metastatic disease) in Switzerland (Transdermal) due to death of 90% of the patients (NCT02067741)
  • 25 Jun 2019 4-Hydroxytestosterone is still in phase II trials for Breast cancer (Late-stage disease) in Switzerland (Transdermal) (NCT02067741)
  • 26 Mar 2014 Curadis plans a phase II trial for Breast cancer (Late-stage disease) in Switzerland (NCT02067741)

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