Drug Profile

Prasinezumab - Prothena Corporation/Roche

Alternative Names: NEOD-002; PRX-002; RG 7935; RO 7046015

Latest Information Update: 28 Jul 2026

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At a glance

Originator Neotope Biosciences
Developer Chugai Pharmaceutical; Prothena; Roche
Class Antiparkinsonians; Monoclonal antibodies; Neuroprotectants
Mechanism of Action Alpha-synuclein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase III Parkinson's disease

Most Recent Events

15 Sep 2025 Hoffmann-La Roche plans to initiate a phase III (PARAISO) trial for Parkinson's disease (Treatment experienced) (IV) in December 2025 (NCT07174310)
08 Jul 2025 University Hospital Tuebingen plans a phase II PreCoDe trial for Parkinson's Disease (In adults, In the elderly) in France, Germany, Italy, Luxembourg, Spain, Sweden and the United Kingdom (IV) (NCT07055087)
16 Jun 2025 Roche plans a phase III trial in Parkinson's disease (Early-stage disease) (IV) in 2025

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