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Research programme: phosphodiesterase inhbitors - Intra-Cellular Therapies

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Drug Profile

Research programme: phosphodiesterase inhbitors - Intra-Cellular Therapies

Alternative Names: ITI 002 series; PDE1 inhbitors - Intra-Cellular Therapies; PDE2 inhibitors - Intra-Cellular Therapies; PDE9 inhibitors - Intra-Cellular Therapies

Latest Information Update: 15 Apr 2025

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At a glance

  • Originator Intra-Cellular Therapies
  • Class Small molecules
  • Mechanism of Action Phosphodiesterase 9A inhibitors; Type 1 cyclic nucleotide phosphodiesterase inhibitors; Type 2 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Alzheimer's disease; Cardiovascular disorders; Neurodegenerative disorders; Schizophrenia

Most Recent Events

  • 02 Apr 2025 Intra-Cellular Therapies has been acquired by Johnson & Johnson
  • 28 Aug 2022 No recent reports of development identified for preclinical development in Cardiovascular-disorders in USA (PO)
  • 28 Aug 2022 No recent reports of development identified for preclinical development in Neurodegenerative-disorders in USA (PO)

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