Elbasvir/grazoprevir - Merck and Co
Alternative Names: Elbasvir and grazoprevir; Grazoprevir/elbasvir; MK-5172/MK-8742; MK-5172A; MK-8742/MK-5172; ZEPATIERLatest Information Update: 05 Nov 2023
At a glance
- Originator Merck & Co
- Class Amides; Antivirals; Benzoxazines; Carbamates; Carboxylic acids; Cyclopropanes; Heterocyclic compounds with 4 or more rings; Imidazoles; Indoles; Macrocyclic compounds; Pyrrolidines; Quinoxalines; Small molecules; Sulfones
- Mechanism of Action Hepatitis C virus NS 5 protein inhibitors; Hepatitis C virus NS3 protein inhibitors; Hepatitis C virus NS4 protein inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Hepatitis C
Most Recent Events
- 31 Dec 2022 University of Pennsylvania and Merck completes a phase I/II trial for Hepatitis C in USA (NCT03724149)
- 28 Sep 2021 No development reported - Phase-III for Hepatitis C (Treatment-naive) in Russia (PO) (NCT02251990)
- 28 Sep 2021 No development reported - Phase-III for Hepatitis C (Treatment-naive) in South Korea (PO) (NCT02251990)