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Elbasvir/grazoprevir - Merck and Co

Drug Profile

Elbasvir/grazoprevir - Merck and Co

Alternative Names: Elbasvir and grazoprevir; Grazoprevir/elbasvir; MK-5172/MK-8742; MK-5172A; MK-8742/MK-5172; ZEPATIER

Latest Information Update: 21 May 2019

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At a glance

  • Originator Merck & Co
  • Class Amides; Antivirals; Benzoxazines; Carbamates; Carboxylic acids; Cyclopropanes; Heterocyclic compounds with 4 or more rings; Imidazoles; Indoles; Macrocyclic compounds; Pyrrolidines; Quinoxalines; Small molecules; Sulfones
  • Mechanism of Action Hepatitis C virus NS 5 protein inhibitors; Hepatitis C virus NS3 protein inhibitors; Hepatitis C virus NS4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hepatitis C

Most Recent Events

  • 12 Dec 2018 University of Pennsylvania and Merck initiates enrolment in a phase I/II trial for Hepatitis C in USA (NCT03724149)
  • 04 Dec 2018 Merck completes a phase III trial in Hepatitis C (treatment-naive) in USA, Germany, Spain, Netherlands, Romania and United Kingdom (NCT02105688)
  • 24 Jun 2018 Biomarkers information updated
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