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Lorecivivint - Samumed

Drug Profile

Lorecivivint - Samumed

Alternative Names: Adavivint; SM-04690

Latest Information Update: 24 May 2019

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At a glance

  • Originator Samumed
  • Class Anti-inflammatories; Antirheumatics; Imidazoles; Indazoles; Pyridines; Small molecules
  • Mechanism of Action Clk dual-specificity kinase inhibitors; DYRK kinase inhibitors; Wnt signalling pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Osteoarthritis
  • Phase I Intervertebral disc degeneration

Most Recent Events

  • 01 May 2019 Phase-III STRIDES-X-ray clinical trial in Osteoarthritis in USA (Intra-articular) (NCT03928184)
  • 23 Apr 2019 Samumed terminates a phase I trial in Intervertebral disc degeneration in USA, due to business reasons (NCT03246399)
  • 11 Apr 2019 Efficacy data from a phase IIb trial in osteoarthritis released by Samumed
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