Crefmirlimab - ImaginAb Inc
Alternative Names: 89-Zr CD8 ImmunoPET minibody - ImaginAb Inc; 89Zr CD8 Immuno-PET agent - ImaginAb; 89Zr-crefmirlimab berdoxam - ImaginAb; 89Zr-Df-crefmirlimab - ImaginAb; 89Zr-Df-IAB22M2C - ImaginAb; [89Zr]-Df-Crefmirlimab; [89Zr]Df-IAB22M2C; CD8 T cell I/O imaging agent; CD8 T Cell imaging agent; CD8-ImmunoPET; IAB 22 M2C; Minibody CD8 T Cell imaging agent; Zirconium 89Zr crefmirlimab berdoxam; Zr-89 IAB22M2CLatest Information Update: 24 Sep 2025
At a glance
- Originator ImaginAb Inc
- Class Antibody diagnostics; Antineoplastics; Diagnostic agents; Imaging agents; Immunoconjugates; Immunoglobulin fragments; Radioisotopes; Radiopharmaceutical diagnostics; Radiopharmaceuticals
- Mechanism of Action Positron-emission tomography enhancers
-
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase III Malignant melanoma; Renal cell carcinoma
- Phase II Inclusion body myositis; Merkel cell carcinoma; Non-small cell lung cancer; Solid tumours
- No development reported Cervical cancer; Gastric cancer; Graft-versus-host disease
Most Recent Events
- 30 May 2025 Updated efficacy data from a phase II trial for Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
- 07 Nov 2024 Jonsson Comprehensive Cancer Center plans a phase I trial for Glioma and Brain cancer in USA (IV) in November 2024(NCT06650163)
- 02 Aug 2024 ImaginAB in collaboration with University Medical Center Groningen plans a phase II trial for Solid tumours (Diagnosis) in Netherlands, Spain and United Kingdom (Parenteral)(NCT06534190)