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Crefmirlimab - ImaginAb Inc

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Drug Profile

Crefmirlimab - ImaginAb Inc

Alternative Names: 89-Zr CD8 ImmunoPET minibody - ImaginAb Inc; 89Zr CD8 Immuno-PET agent - ImaginAb; 89Zr-crefmirlimab berdoxam - ImaginAb; 89Zr-Df-crefmirlimab - ImaginAb; 89Zr-Df-IAB22M2C - ImaginAb; [89Zr]-Df-Crefmirlimab; [89Zr]Df-IAB22M2C; CD8 T cell I/O imaging agent; CD8 T Cell imaging agent; CD8-ImmunoPET; IAB 22 M2C; Minibody CD8 T Cell imaging agent; Zirconium 89Zr crefmirlimab berdoxam; Zr-89 IAB22M2C

Latest Information Update: 03 Mar 2026

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At a glance

  • Originator ImaginAb Inc
  • Class Antibody diagnostics; Antineoplastics; Diagnostic agents; Imaging agents; Immunoconjugates; Immunoglobulin fragments; Radioisotopes; Radiopharmaceutical diagnostics; Radiopharmaceuticals
  • Mechanism of Action Positron-emission tomography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Malignant melanoma; Renal cell carcinoma
  • Phase II Inclusion body myositis; Merkel cell carcinoma; Non-small cell lung cancer; Solid tumours
  • No development reported Cervical cancer; Gastric cancer; Graft-versus-host disease

Most Recent Events

  • 03 Mar 2026 Crefmirlimab is still in phase III trials for Malignant Melanoma in United Kingdom
  • 03 Mar 2026 Crefmirlimab is still in phase III trials for Renal cell carcinoma in United Kingdom
  • 30 May 2025 Updated efficacy data from a phase II trial for Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)

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