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CXA 10

Drug Profile

CXA 10

Alternative Names: 10-nitro-oleic-acid; CXA-10

Latest Information Update: 20 Nov 2019

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At a glance

  • Originator Complexa
  • Class Antihypertensives; Nitro compounds; Oleic acids; Small molecules; Unsaturated fatty acids; Urologics
  • Mechanism of Action Heat-shock protein stimulants; NF E2 related factor 2 stimulants; NF-kappa B inhibitors; Toll-like receptor 4 antagonists; Xanthine dehydrogenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary arterial hypertension
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Focal segmental glomerulosclerosis; Pulmonary arterial hypertension
  • No development reported Acute kidney injury; Renal failure

Most Recent Events

  • 31 Oct 2019 Complexa initiates enrolment in a phase II trial for Pulmonary arterial hypertension (In Adults, In the elderly) in USA (NCT04125745)
  • 17 Oct 2019 Complexa plans a phase IIa trial for Pulmonary arterial hypertension in USA in October 2019 (NCT04125745)
  • 04 Oct 2019 CXA 10 receives Orphan Drug status for Pulmonary arterial hypertension in USA
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