Ibcasertib - Chipscreen Biosciences
Alternative Names: Aurora B/VEGFR/PDGFR /c-Kit/CSF1R inhibitor; Chiauranib; Chiauranib - Chipscreen Biosciences; CS-2164; IbcasertibLatest Information Update: 18 Jul 2024
At a glance
- Originator Chipscreen Biosciences
- Class Amides; Aniline compounds; Antineoplastics; Ethers; Naphthalenes; Quinolines; Small molecules
- Mechanism of Action Angiogenesis inhibitors; Aurora kinase B inhibitors; Macrophage colony-stimulating factor receptor antagonists; Mitosis inhibitors; Platelet-derived growth factor alpha receptor antagonists; Proto-oncogene protein c-kit inhibitors; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists; Vascular endothelial growth factor receptor-3 antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Ovarian cancer; Peritoneal cancer; Small cell lung cancer
- Phase II Graft-versus-host disease; Non-Hodgkin's lymphoma; Soft tissue sarcoma; Triple negative breast cancer
- Phase I/II Liver cancer
- Preclinical Pancreatic cancer
- No development reported Solid tumours
Most Recent Events
- 09 Jul 2024 Chipscreen Biosciences plans a phase II trial for Adenocarcinoma (Late-stage disease, Metastatic disease, Combination therapy, First-line therapy, Inoperable/Unresectable) (PO) in August 2024 (NCT06492915)
- 18 Mar 2024 Chipscreen Biosciences completes a clinical trial in Small cell lung cancer in China (PO) (NCT05371899)
- 02 Jan 2024 Phase-II clinical trials in Graft-versus-host disease (PO) (Chipscreen Biosciences pipeline, January 2024)