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MK 4166

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Drug Profile

MK 4166

Alternative Names: Anti-GITR antibody - Merck; MK-4166

Latest Information Update: 28 Apr 2022

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At a glance

  • Originator Merck & Co
  • Developer Bristol-Myers Squibb; Merck & Co
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Immunomodulators; TNFRSF18 protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Glioblastoma; Solid tumours

Most Recent Events

  • 28 Apr 2022 No recent reports of development identified for phase-I development in Glioblastoma(Combination therapy, Recurrent, Second-line therapy or greater) in USA (IV)
  • 02 Jul 2020 Bristol-Myers Squibb and Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins terminates phase I trial in Glioblastoma due to funding or material support withdrawn in USA (NCT03707457)
  • 28 Nov 2019 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Metastatic disease) in Australia (IV, Infusion)

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