Drug Profile

LTI 291

Alternative Names: BIA 28-6156/LTI-291; LTI-00291; LTI-291

Latest Information Update: 15 Oct 2025

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At a glance

Originator Lysosomal Therapeutics
Developer BIAL; Lysosomal Therapeutics
Class Amides; Antiparkinsonians; Cyclohexanes; Ethers; Pyrazoles; Pyrimidines; Small molecules
Mechanism of Action Glucosylceramidase stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Parkinson's disease

Most Recent Events

15 Oct 2025 Chemical structure information added.
25 Aug 2025 Phase-I clinical trials in Parkinson's disease in Hungary (PO) (CTIS2025-520754-11-00)
28 Jan 2025 No recent reports of development identified for phase-I development in Parkinson's-disease(In volunteers) in United Kingdom (PO)

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