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Fluciclovine 18F - Emory University/GE Healthcare/Nihon Medi-Physics

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Drug Profile

Fluciclovine 18F - Emory University/GE Healthcare/Nihon Medi-Physics

Alternative Names: 18F-Ge-148; 18F fluciclovine; [18F]-FACBC; Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic-acid; Anti-1-amino-3-F-18-fluorocyclobutane-1-carboxylic-acid; Anti-1-amino-3-fluorine-18-fluorocyclobutane-1-carboxylic acid; Anti-18-F-FACBC; Anti-18F-FABC; Anti-3-18F-FACBC; Anti-F-18-fluorocyclobutane-carboxylic-acid; Axumin; Axumin-PET scan; FACBC; fluciclovine(18F); Fluciclovine-F-18; GE-148; Ge-148-18F; Ge-148-F-18; NMK-36; Trans-1-amino-3-18F-fluorocyclobutanecarboxylic-acid

Latest Information Update: 01 Oct 2024

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At a glance

  • Originator Emory University
  • Developer Blue Earth Diagnostics; Emory University; GE Healthcare; Memorial Sloan-Kettering Cancer Center; Nihon Medi-Physics; University of Arizona
  • Class Amino acids; Carboxylic acids; Cyclobutanes; Imaging agents; Radiopharmaceutical diagnostics; Small molecules
  • Mechanism of Action Positron-emission tomography enhancers; Radionuclide imaging enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioma
  • New Molecular Entity No

Highest Development Phases

  • Marketed Prostate cancer
  • Preregistration Glioma
  • Phase III Brain metastases
  • Phase II Bone metastases
  • Phase I Breast cancer
  • No development reported Glioblastoma; Head and neck cancer; Lung cancer; Parathyroid cancer

Most Recent Events

  • 01 Oct 2024 Fluciclovine 18F - Emory University/GE Healthcare/Nihon Medi-Physics is still in phase I trials for Breast cancer (Diagnosis) in USA (IV, Injection)
  • 28 Sep 2024 No recent reports of development identified for phase-I development in Breast-cancer(Diagnosis) in USA (IV, Injection)
  • 21 Mar 2024 Emory University in collaboration with National Cancer Institute completes a phase-I trials in Breast cancer (Diagnosis) in USA (IV) (NCT04750473)

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