Dronedarone/ranolazine - Gilead Sciences

Drug Profile

Dronedarone/ranolazine - Gilead Sciences

Alternative Names: Ranolazine/dronedarone

Latest Information Update: 16 Mar 2017

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At a glance

  • Originator Gilead Sciences
  • Class Acetanilides; Anti-ischaemics; Benzofurans; Class III antiarrhythmics; Ischaemic heart disorder therapies; Piperazines; Small molecules
  • Mechanism of Action Partial fatty acid oxidation inhibitors; Potassium channel antagonists; Pyruvate dehydrogenase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Paroxysmal atrial fibrillation

Most Recent Events

  • 16 Mar 2017 Discontinued - Phase-II for Paroxysmal atrial fibrillation in USA, United Kingdom, Poland, Netherlands, Italy, Israel, and Germany (PO), because dronedarone/ranolazine was not listed on Gilead pipeline of March 2017
  • 10 May 2014 Final efficacy data from the phase II HARMONY trial in Paroxysmal atrial fibrillation released by Gilead Sciences
  • 31 Mar 2014 Gilead Sciences completes the phase II HARMONY trial in Paroxysmal atrial fibrillation in USA, Germany, Israel, Italy, Netherlands, Poland and United Kingdom (NCT01522651)
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