Drug Profile

Eicosapentaenoic acid/metformin

Alternative Names: Eicosapentaenoate/metformin; Metformin/eicosapentaenoate; Metformin/eicosapentaenoic acid; TP-101

Latest Information Update: 22 Mar 2016

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At a glance

Originator Thetis Pharmaceuticals
Class Antihyperglycaemics; Antihyperlipidaemics; Biguanides; Eicosanoids; Omega 3 fatty acids; Small molecules
Mechanism of Action AMP activated protein kinase stimulants; Gluconeogenesis inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

22 Mar 2016 No recent reports on development identified - Phase-I for Hypertriglyceridaemia (In volunteers) in USA (PO)
22 Mar 2016 No recent reports on development identified - Phase-I for Type-2 diabetes mellitus (In volunteers) in USA (PO)
01 Jul 2014 Discontinued - Phase-I for Hypertriglyceridaemia (In volunteers) in USA (PO) (NCT02113163)

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