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ODN/Pam2 - Pulmotect

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Drug Profile

ODN/Pam2 - Pulmotect

Alternative Names: ODN-M362/Pam2CSK4; Pam2-ODN; Pam2/ODN; Pam2CSK4/ODN-M362; PUL-042

Latest Information Update: 16 May 2025

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At a glance

  • Originator Pulmotect
  • Developer Cancer Prevention & Research Institute of Texas; National Heart, Lung and Blood Institute; Pulmotect; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Antisense oligonucleotides; Antivirals; Lipopeptides
  • Mechanism of Action Toll-like receptor 2 agonists; Toll-like receptor 6 agonists; Toll-like receptor 9 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Chronic obstructive pulmonary disease; COVID 2019 infections; Lung disorders
  • Preclinical Invasive bronchopulmonary aspergillosis
  • No development reported Haematological malignancies; Pneumocystis pneumonia

Most Recent Events

  • 24 Apr 2025 Phase-II clinical trials in Lung disorders (Treatment-experienced) in USA (Inhalation) (NCT06665100)
  • 30 Oct 2024 Pulmotect plans a phase II trial in Lung disorders (Treatment-experienced) in USA (Inhalation) in October 2025 (NCT06665100)
  • 16 Oct 2024 Pharmacodynamics data from a preclinical trial in Lung disorders presented at the IDWeek 2024 (IDW-2024)

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