Efinopegdutide - Hanmi Pharmaceutical
Alternative Names: GLP-1/glucagon-agonist; Glucagon-like-peptides/glucagon; Glucagon/GLP-1-agonist; HM-12525A; JNJ 5111; JNJ-64565111; LAPS GLP/GCG; LAPS-GCG/GLP-1; LAPS-GLP-1/GCG; LAPS-GLP/GCG agonist; LAPS-GLP/Glucagon; LAPS-OXM; MK-6024; Oxyntomodulin immunoglobulin conjugateLatest Information Update: 05 Aug 2026
At a glance
- Originator Hanmi Pharmaceutical
- Developer Hanmi Pharmaceutical; Janssen Pharmaceuticals; Merck & Co
- Class Antihyperglycaemics; Glucagon-like peptides; Hepatoprotectants; Immunoglobulin Fc fragments; Obesity therapies; Recombinant fusion proteins
- Mechanism of Action Glucagon receptor agonists; Glucagon-like peptide-1 receptor agonists
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Liver cirrhosis; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis
- Discontinued Obesity; Type 2 diabetes mellitus
Most Recent Events
- 05 Aug 2026 Hanmi Pharmaceuticals has patent protection for conjugate comprising oxyntomodulin and an immunoglobulin fragment, and use thereof in the US and multiple locations in the World
- 04 Aug 2026 Hanmi Pharmaceuticals plans a phase III trial for Non-alcoholic steatohepatitis in 2027
- 29 Dec 2025 Merck Sharp & Dohme completes a phase II trial in Non-alcoholic steatohepatitis in The US, Austria, Belgium, Canada, Chile, China, Colombia, Czechia, France, Hong-Kong, Hungary, Israel, Italy, Japan, Mexico, Peru, Portugal, Puerto Rico, Singapore, South Korea, Spain, Switzerland, Taiwan, Thailand, Turkey and the United Kingdom (SC) (NCT05877547)