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Mavacamten - Bristol Myers Squibb/MyoKardia

Drug Profile

Mavacamten - Bristol Myers Squibb/MyoKardia

Alternative Names: BMS-986427; CAMZYOS; Camzyos; CamzyosTM; HCM 1; MAVA-Bristol Myers Squibb/Myokardia; MYK 461; SAR-439152

Latest Information Update: 27 Mar 2024

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At a glance

  • Originator MyoKardia
  • Developer Bristol-Myers Squibb; LianBio; MyoKardia
  • Class Cardiovascular therapies; Ethylamines; Heart failure therapies; Pyrimidinones; Small molecules
  • Mechanism of Action Cardiac myosin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypertrophic cardiomyopathy
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hypertrophic cardiomyopathy
  • Phase II Heart failure

Most Recent Events

  • 25 Mar 2024 Registered for Hypertrophic cardiomyopathy in Hong Kong (PO) prior to March 2024
  • 08 Mar 2024 Phase-III clinical trials in Hypertrophic cardiomyopathy (In adolescents, In children) in USA, Spain (PO) (NCT06253221)
  • 15 Feb 2024 Bristol-Myers Squibb plans a phase III trial for Hypertrophic cardiomyopathy (In children, In adolescent) in USA, Canada, France, Germany, Ireland, Italy, Spain, the UK and Australia (PO, Capsule) (NCT06253221)
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