Mavacamten - MyoKardia

Drug Profile

Mavacamten - MyoKardia

Alternative Names: HCM 1; MYK-461; SAR-439152

Latest Information Update: 28 Jul 2018

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At a glance

  • Originator MyoKardia
  • Class Cardiovascular therapies; Small molecules
  • Mechanism of Action Myosin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypertrophic cardiomyopathy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Hypertrophic cardiomyopathy

Most Recent Events

  • 28 Jul 2018 No recent reports of development identified for phase-I development in Hypertrophic-cardiomyopathy(In volunteers) in United Kingdom (PO)
  • 30 May 2018 Phase-III clinical trials in Hypertrophic cardiomyopathy in USA (PO) (NCT03470545)
  • 08 May 2018 MyoKardia plans a long-term extension (LTE) trial of patients who complete the phase III EXPLORER-HCM or the phase II MAVERICK-HCM trial for Hypertrophic cardiomyopathy by the end of 2018
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