Nitric oxide inhalation - INOpulse - Bellerophon Therapeutics

Drug Profile

Nitric oxide inhalation - INOpulse - Bellerophon Therapeutics

Alternative Names: Inhaled nitric oxide - Bellerophon; inhaled NO; iNO- Bellerophon; Nitric oxide-INOpulse

Latest Information Update: 04 Jul 2018

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At a glance

  • Originator Ikaria Holdings
  • Developer Bellerophon Therapeutics
  • Class Anti-inflammatories; Antiacnes; Antiandrogens; Antibacterials; Antifibrotics; Antifungals; Antihypertensives; Antivirals; Free radicals; Macromolecular substances; Nitrogen oxides; Non-opioid analgesics; Small molecules; Vasodilators
  • Mechanism of Action Guanylate cyclase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary arterial hypertension
  • New Molecular Entity No

Highest Development Phases

  • Phase III Pulmonary arterial hypertension
  • Phase II Pulmonary hypertension

Most Recent Events

  • 18 May 2018 Updated efficacy data from a phase II trial in Pulmonary hypertension presented at the 114th International Conference of the American Thoracic Society (ATS-2018)
  • 10 May 2018 Ikaria Hldings and Bellerophon expand licensing agreement for Nitric oxide inhalation to include Interstitial lung diseases
  • 10 May 2018 Bellerophon plans a phase IIb trial for Pulmonary hypertension (associated with chronic obstructive pulmonary disease) in USA
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