Acamprosate/baclofen - Pharnext

Drug Profile

Acamprosate/baclofen - Pharnext

Alternative Names: Acamprosate/baclofen; PXT 864

Latest Information Update: 27 Sep 2017

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At a glance

  • Originator BioSystems International; INSERM; Pharnext; University of Bordeaux
  • Developer Pharnext
  • Class Alkanesulfonic-acids; Aminobutyric acids; Antiparkinsonians; Antispastics; Muscle relaxants; Nootropics; Small molecules
  • Mechanism of Action GABA B receptor agonists; GABA receptor agonists; Glutamate receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Alzheimer's disease
  • Phase I Amyotrophic lateral sclerosis; Parkinson's disease
  • Discontinued Memory disorders

Most Recent Events

  • 26 Sep 2017 PXT 864 is still in phase II trials for Alzheimer's disease in France (Pharnext website, September 2017)
  • 16 Jul 2017 Efficacy and adverse events data from the phase II PLEODIAL trial in Alzheimer's disease presented at the Alzheimer's Association International Conference 2017 (AAIC-2017)
  • 26 May 2017 Chemical structure information added
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