Research programme: SNA based therapeutics - Exicure

Drug Profile

Research programme: SNA based therapeutics - Exicure

Alternative Names: SNA constructs - Exicure; SNA targeting IL17RA - Exicure; SNA targeting IL4RA - Exicure; Spherical nucleic acid constructs - Exicure

Latest Information Update: 12 Jul 2018

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At a glance

  • Originator AuraSense Therapeutics
  • Developer Exicure
  • Class Anti-inflammatories; Antifibrotics; Antineoplastics; Antipsoriatics; Eye disorder therapies; Nucleic acids; Skin disorder therapies
  • Mechanism of Action Gene modulators; HD protein inhibitors; Immunomodulators; Immunosuppressants; Interleukin 1 beta modulators; Interleukin 4 receptor modulators; Survival of motor neuron 2 protein expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Eye-Disorders; Huntington's disease; Inflammatory bowel diseases; Respiration disorders; Spinal muscular atrophy
  • Discontinued Atopic dermatitis; Brain cancer; Epidermolysis bullosa; Fibrosis; Lymphoma; Transplant rejection

Most Recent Events

  • 12 Jul 2018 Discontinued - Preclinical for Atopic dermatitis in USA (unspecified route)
  • 12 Jul 2018 Discontinued - Preclinical for Brain cancer in USA (unspecified route)
  • 12 Jul 2018 Discontinued - Preclinical for Fibrosis in USA (unspecified route)
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