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Ulonivirine - Merck Sharp & Dohme

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Drug Profile

Ulonivirine - Merck Sharp & Dohme

Alternative Names: MK-8507

Latest Information Update: 25 Apr 2026

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At a glance

  • Originator Merck Sharp & Dohme
  • Class Antiretrovirals; Benzonitrile; Chlorinated hydrocarbons; Ethers; Fluorinated hydrocarbons; Pyridazines; Pyrimidines; Small molecules
  • Mechanism of Action Non-nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II HIV-1 infections

Most Recent Events

  • 15 Apr 2026 Merck Sharp & Dohme plans a phase I (MK-8507-018) pharmacokinetics trial in Healthy volunteers (PO, Tablet) in May 2026 (NCT07530289)
  • 09 Apr 2026 Merck Sharp & Dohme completes a phase I trial for HIV-1 infections (In volunteers) in USA (PO, Tablet) (NCT07305831)
  • 22 Jan 2026 Merck Sharp & Dohme initiates a phase I trial for HIV-1 infections (In volunteers) in USA (PO, Tablet) (NCT07305831)

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