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Monepantel - PharmAust

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Drug Profile

Monepantel - PharmAust

Alternative Names: NUZ-001; PPL-1; S-Monepantel

Latest Information Update: 23 Dec 2024

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At a glance

  • Originator Pitney Pharmaceuticals
  • Developer PharmAust
  • Class Acetonitriles; Anthelmintics; Antineoplastics
  • Mechanism of Action Cyclin-dependent kinase 2 modulators; Cyclin-dependent kinase 4 modulators; TDP-43 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Solid tumours
  • Phase I Amyotrophic lateral sclerosis; Motor neuron disease

Most Recent Events

  • 18 Dec 2024 Neurizon Therapeutics files an IND application for phase II/III HEALEY ALS trial with the US FDA for Amyotrophic lateral sclerosis
  • 18 Dec 2024 Neurizon Therapeutics plans a phase II/III HEALEY ALS trial for Amyotrophic lateral sclerosis in USA in 1H 2025 ,
  • 20 Nov 2024 Pharmacodynamics data from a preclinical studies in Amyotrophic lateral sclerosis released by Neurizon Therapeutics

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