Drug Profile

MK 8189

Alternative Names: MK-8189

Latest Information Update: 12 Mar 2025

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At a glance

Originator Merck Sharp & Dohme
Class Antidementias; Antipsychotics
Mechanism of Action Phosphodiesterase 10A inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Discontinued Alzheimer's disease; Bipolar disorders; Schizophrenia

Most Recent Events

31 Dec 2024 Discontinued - Phase-I for Alzheimer's disease (In the elderly) in USA (PO)
31 Dec 2024 Discontinued - Phase-I for Bipolar disorders in USA (PO)
31 Dec 2024 Discontinued - Phase-II for Schizophrenia in USA (PO)

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