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MK 8189

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Drug Profile

MK 8189

Alternative Names: MK-8189

Latest Information Update: 26 Jul 2024

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At a glance

  • Originator Merck Sharp & Dohme
  • Class Antidementias; Antipsychotics
  • Mechanism of Action Phosphodiesterase 10A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Schizophrenia
  • Phase I Alzheimer's disease; Bipolar disorders

Most Recent Events

  • 21 Jun 2024 Merck Sharp & Dohme Corp completes a phase IIb trial in Schizophrenia in Bulgaria, Croatia, Japan, Latvia, Poland, Romania, Russia, Serbia, South Korea, Taiwan, Ukraine and USA (PO, Tablet) (NCT04624243)
  • 08 Apr 2024 Phase-I clinical trials in Bipolar disorders in USA (PO) (NCT06273774)
  • 23 Feb 2024 Merck Sharp & Dohme plans a phase I trial for Bipolar I disorder in March 2024 (NCT06273774)

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