Tolcapone - Corino Therapeutics/SOM Biotech

Drug Profile

Tolcapone - Corino Therapeutics/SOM Biotech

Alternative Names: CRX-1008; SOM 0226

Latest Information Update: 27 Jul 2017

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At a glance

  • Originator SOM Biotech
  • Developer SOM Biotech; Vall d-Hebron Research Institute
  • Class Antiparkinsonians; Benzophenones; Nitrophenols; Small molecules
  • Mechanism of Action Catechol-O-methyltransferase inhibitors; Prealbumin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyloid polyneuropathy
  • New Molecular Entity No
  • Available For Licensing Yes - Amyloid polyneuropathy

Highest Development Phases

  • Phase II Amyloid polyneuropathy

Most Recent Events

  • 19 Jul 2018 Corino Therapeutics plans an early phase I trial for Amyloidosis in USA (NCT03591757)
  • 22 May 2017 Tolcapone licensed to Corino Therapeutics worldwide
  • 31 Mar 2017 Phase-II development for Amyloid polyneuropathy is ongoing in Spain (PO)
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