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Malaria vaccine live unattenuated plus chloroquine - Sanaria

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Drug Profile

Malaria vaccine live unattenuated plus chloroquine - Sanaria

Alternative Names: PfSPZ Challenge plus chloroquine; PfSPZ CVac; PfSPZ malaria vaccine live unattenuated plus chloroquine - Sanaria; Plasmodium falciparum sporozoite vaccine live unattenuated plus chloroquine - Sanaria

Latest Information Update: 25 Dec 2024

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At a glance

  • Originator Sanaria
  • Developer National Institute of Allergy and Infectious Diseases; Sanaria; University of Tubingen
  • Class Antimalarials; Parasitic vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Falciparum malaria

Most Recent Events

  • 23 May 2024 The US FDA places a clinical hold on PfSPZ Challenge (NCT04280692)
  • 23 May 2024 University of Oxford in collaboration with Sanaria suspends the phase I/II CHMI-TransMod trial in Falciparum malaria (In volunteers, Prevention) in Kenya (IV) (NCT04280692)
  • 22 Aug 2022 Phase-I/II clinical trials in Falciparum malaria (In volunteers, Prevention) in Kenya (IV) (NCT04280692)

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