Perflenapent - NuvOX Pharma
Alternative Names: DDFPe; Dodecafluoropentane; NanO2; NVX 208; NVX-108; Perfluorocarbon; Perfluoropentane; PFPLatest Information Update: 02 Dec 2025
At a glance
- Originator NuvOx Pharma
- Class Anti-ischaemics; Antianaemics; Antihaemorrhagics; Antineoplastics; Fluorocarbons; Neuroprotectants; Radiation-sensitising agents; Radiosensitisers; Small molecules; Vascular disorder therapies
- Mechanism of Action Oxygen carriers
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Orphan Drug Status
Yes - Sickle cell anaemia; Glioblastoma
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase II Adult respiratory distress syndrome; Glioblastoma; Stroke
- Phase I Respiratory distress syndrome
- Preclinical Haemorrhagic shock; Myocardial infarction; Traumatic brain injuries
- No development reported SARS-CoV-2 acute respiratory disease; Sickle cell anaemia; Triple negative breast cancer
Most Recent Events
- 19 Nov 2025 FYR Bio and NuvOx Therapeutics receives SBIR grant from the National Cancer Institute (NCI) for perflenapent development in glioblastoma
- 19 Nov 2025 Phase-II clinical trials in Stroke (Parenteral) prior to November 2025
- 06 Nov 2025 Efficacy and adverse events data from phase Ib trial in Respiratory distress syndrome released by NuvOx Pharma