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Perflenapent - NuvOX Pharma

Drug Profile

Perflenapent - NuvOX Pharma

Alternative Names: DDFPe; Dodecafluoropentane; dodecafluoropentane emulsion; NanO2; NVX 208; NVX-108; Perfluorocarbon; Perfluoropentane; PFP

Latest Information Update: 11 Aug 2026

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At a glance

  • Originator Achieve Life Sciences
  • Developer NuvOx Pharma
  • Class Anti-ischaemics; Antianaemics; Antihaemorrhagics; Antineoplastics; Fluorocarbons; Neuroprotectants; Radiation-sensitising agents; Radiosensitisers; Small molecules; Vascular disorder therapies
  • Mechanism of Action Oxygen carriers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sickle cell anaemia; Glioblastoma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Adult respiratory distress syndrome; Glioblastoma; Ischaemic stroke; Stroke
  • Phase I Respiratory distress syndrome
  • Preclinical Haemorrhagic shock; Myocardial infarction; Traumatic brain injuries
  • No development reported SARS-CoV-2 acute respiratory disease; Sickle cell anaemia; Triple negative breast cancer

Most Recent Events

  • 05 Aug 2026 NuvOx LLC initiated an Expanded Access program for the treatment of Glioblastoma (NCT07748299)
  • 20 Jul 2026 US FDA approves IND application for NanO2 in Glioma
  • 20 Jul 2026 NuvOx completes enrolment in phase-II clinical trials in Glioblastoma (Combination therapy, First-line therapy) in USA (IV) (NCT03862430)

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