Perflenapent - NuvOX Pharma
Alternative Names: DDFPe; Dodecafluoropentane; dodecafluoropentane emulsion; NanO2; NVX 208; NVX-108; Perfluorocarbon; Perfluoropentane; PFPLatest Information Update: 11 Aug 2026
At a glance
- Originator Achieve Life Sciences
- Developer NuvOx Pharma
- Class Anti-ischaemics; Antianaemics; Antihaemorrhagics; Antineoplastics; Fluorocarbons; Neuroprotectants; Radiation-sensitising agents; Radiosensitisers; Small molecules; Vascular disorder therapies
- Mechanism of Action Oxygen carriers
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Orphan Drug Status
Yes - Sickle cell anaemia; Glioblastoma
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase II Adult respiratory distress syndrome; Glioblastoma; Ischaemic stroke; Stroke
- Phase I Respiratory distress syndrome
- Preclinical Haemorrhagic shock; Myocardial infarction; Traumatic brain injuries
- No development reported SARS-CoV-2 acute respiratory disease; Sickle cell anaemia; Triple negative breast cancer
Most Recent Events
- 05 Aug 2026 NuvOx LLC initiated an Expanded Access program for the treatment of Glioblastoma (NCT07748299)
- 20 Jul 2026 US FDA approves IND application for NanO2 in Glioma
- 20 Jul 2026 NuvOx completes enrolment in phase-II clinical trials in Glioblastoma (Combination therapy, First-line therapy) in USA (IV) (NCT03862430)