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Perflenapent - NuvOX Pharma

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Drug Profile

Perflenapent - NuvOX Pharma

Alternative Names: DDFPe; Dodecafluoropentane; NanO2; NVX 208; NVX-108; Perfluorocarbon; Perfluoropentane; PFP

Latest Information Update: 24 Jun 2025

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At a glance

  • Originator NuvOx Pharma
  • Class Anti-ischaemics; Antianaemics; Antihaemorrhagics; Antineoplastics; Fluorocarbons; Neuroprotectants; Radiation-sensitising agents; Radiosensitisers; Small molecules; Vascular disorder therapies
  • Mechanism of Action Oxygen carriers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sickle cell anaemia; Glioblastoma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Adult respiratory distress syndrome; Glioblastoma; Stroke
  • Phase I Respiratory distress syndrome
  • Preclinical Haemorrhagic shock; Myocardial infarction; SARS-CoV-2 acute respiratory disease; Sickle cell anaemia; Traumatic brain injuries; Triple negative breast cancer

Most Recent Events

  • 12 Jun 2025 Phase-II clinical trials in Adult respiratory distress syndrome (IV)
  • 13 Mar 2025 Phase-I clinical trials in Respiratory distress syndrome in Canada (IV) (NCT06658535)
  • 04 Mar 2025 US FDA approves IND application for Perflenapent for phase-II GNOSTIC trial in Myocardial infarction

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