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Pilocarpine - AbbVie

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Drug Profile

Pilocarpine - AbbVie

Alternative Names: AGN-190584; pilocarpine 1.25%; Pilocarpine 1.25% ophthalmic solution - AbbVie; Pilocarpine HCl 1.25%; VUITY

Latest Information Update: 09 Feb 2026

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At a glance

  • Originator Allergan
  • Developer AbbVie; Allergan
  • Class Alkaloids; Antiglaucomas; Eye disorder therapies; Furans; Imidazoles; Ketones; Miotics; Small molecules
  • Mechanism of Action Muscarinic receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Presbyopia

Most Recent Events

  • 09 Feb 2026 Discontinued - Phase-III for Presbyopia in Australia (Ophthalmic) (AbbVie pipeline; February 2026)
  • 29 Jun 2022 Allergan withdraws a phase II ARIES trial for Presbyopia in USA (Ophthalmic, Drops) (NCT05393089)
  • 23 May 2022 Allergan plans a phase II ARIES trial for Presbyopia in USA (Ophthalmic, Drops) (NCT05393089)

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