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Soticlestat - Takeda

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Drug Profile

Soticlestat - Takeda

Alternative Names: OV-935; TAK 935

Latest Information Update: 01 Oct 2024

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At a glance

  • Originator Takeda
  • Class Analgesics; Antiepileptic drugs; Heterocyclic compounds; Piperidines; Pyridines; Small molecules
  • Mechanism of Action Cholesterol 24-hydroxylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Lennox-Gastaut syndrome; Dravet syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Dravet syndrome
  • Phase II Complex regional pain syndromes
  • Discontinued Lennox-Gastaut syndrome

Most Recent Events

  • 14 Aug 2024 Takeda terminates a phase III trial in Lennox-Gastaut syndrome and Dravet syndrome (In adolescents, In children, In adults) in Denmark (PO), due to business decision (NCT06422377)
  • 13 Aug 2024 Discontinued - Phase-II for Lennox-Gastaut syndrome (In adolescents, Adjunctive treatment, In children, In adults) in Portugal, Israel (PO)
  • 13 Aug 2024 Discontinued - Phase-III for Lennox-Gastaut syndrome (Adjunctive treatment, In adolescents, In adults, In children) in Serbia (PO)

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