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5-Hydroxytriptolide - Shanghai Institute of Materia Medica/Shanghai Pharmaceuticals Holding

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Drug Profile

5-Hydroxytriptolide - Shanghai Institute of Materia Medica/Shanghai Pharmaceuticals Holding

Alternative Names: 5(R)-5-hydroxytriptolide; Leitengshu; LLDT-8; LLDT-8 cpd; LTS - Shanghai Pharmaceuticals Holding; T8

Latest Information Update: 25 Jul 2022

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At a glance

  • Originator Shanghai Institute of Materia Medica
  • Developer Shanghai Pharmaceuticals Holding
  • Class Anti-inflammatories; Antineoplastics; Antiretrovirals; Antirheumatics; Diterpenes; Herbal medicines
  • Mechanism of Action Immunostimulants; Interferon-gamma expression inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II HIV infections
  • Phase I/II Rheumatoid arthritis

Most Recent Events

  • 25 Jul 2022 Phase-II development in HIV infections is ongoing in China (PO) (NCT04084444)
  • 05 Jul 2022 Shanghai Pharmaceuticals Holding completes a phase II trial in HIV infections in China (PO) (NCT04084444)
  • 30 Jun 2019 Phase-II clinical trials in HIV infections in China (PO) (NCT04084444)

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