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Dubermatinib - Sumitomo Pharma America

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Drug Profile

Dubermatinib - Sumitomo Pharma America

Alternative Names: TP-0903

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator Tolero Pharmaceuticals
  • Developer Sumitomo Pharma America; Tolero Pharmaceuticals
  • Class Aniline compounds; Antineoplastics; Piperazines; Pyrimidines; Small molecules; Sulfonamides
  • Mechanism of Action Aurora kinase B inhibitors; Axl receptor tyrosine kinase inhibitors; Janus kinase 2 inhibitors; STAT6 transcription factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Acute myeloid leukaemia; Chronic lymphocytic leukaemia
  • No development reported Breast cancer; Glioblastoma; Head and neck cancer; Lung cancer; Malignant melanoma; Neuroblastoma; Solid tumours

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy) in USA (PO)
  • 28 Jun 2025 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Second-line therapy or greater) in Japan (PO)
  • 28 Jun 2025 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO)

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