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MVA Brachyury TRICOM vaccine - Bavarian Nordic

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Drug Profile

MVA Brachyury TRICOM vaccine - Bavarian Nordic

Alternative Names: BN-Brachyury; Brachyury/TRICOM; MVA-BN-Brachyury vaccine; MVA-BN-Brachyury/ FPV-Brachyury; MVA-brachyury-TRICOM

Latest Information Update: 26 Nov 2024

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At a glance

  • Originator Bavarian Nordic
  • Developer Bavarian Nordic; National Cancer Institute (USA); University of Utah
  • Class Antineoplastics; Cancer vaccines; Immunotherapies
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chordoma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Chordoma
  • Phase I/II Prostate cancer; Solid tumours

Most Recent Events

  • 08 Oct 2024 National Cancer Institute completes a QuEST1 phase-I/II clinical trial in Prostate cancer (Combination therapy, Hormone-refractory, Late-stage disease) in the USA (SC) (NCT03493945)
  • 08 Oct 2024 National Cancer Institute completes the QuEST1 phase I/II trial for Solid tumours (Combination therapy, Metastatic disease, Second line therapy or greater) in USA (SC)(NCT03493945)
  • 13 Sep 2024 Efficacy and adverse event data from the phase I/II QuEST1 trial in Prostate cancer presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)

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