JTCR 016
Alternative Names: High-affinity WT1-specific TCR T cells - Juno Therapeutics; HLA-A2/WT1-specific TCR T cells - Juno Therapeutics; JTCR016; WT1 TCR-transduced T-cell therapy - Juno Therapeutics; WT1-sensitised T cells - Juno TherapeuticsLatest Information Update: 02 Aug 2019
At a glance
- Originator Juno Therapeutics
- Developer Fred Hutchinson Cancer Research Center; Juno Therapeutics
- Class Gene therapies; Immunotherapies; T lymphocyte cell therapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I/II Chronic myeloid leukaemia; Mesothelioma; Myelodysplastic syndromes; Non-small cell lung cancer; Precursor cell lymphoblastic leukaemia-lymphoma
Most Recent Events
- 02 Aug 2019 Phase I/II development is ongoing in USA
- 06 Mar 2018 Juno Therapeutics has been acquired by Celgene Corporation
- 22 Mar 2017 Juno Therapeutics plans a third phase I/II trial for Acute myeloid leukaemia in USA