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Mezagitamab - Takeda

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Drug Profile

Mezagitamab - Takeda

Alternative Names: Anti-CD38 mAb; TAK-079

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator Takeda
  • Class Antineoplastics; Antirheumatics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma; Idiopathic thrombocytopenic purpura
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Idiopathic thrombocytopenic purpura
  • Phase II Multiple myeloma; Myasthenia gravis
  • Phase I/II Systemic lupus erythematosus
  • No development reported IgA nephropathy
  • Discontinued Rheumatoid arthritis

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in IgA-nephropathy in USA (SC, Injection)
  • 09 May 2025 Takeda plans a phase III trial for IgA nephropathy (Combination therapy, Treatment-experienced) (SC, Injection) in August 2025 (NCT06963827) (EUCT2025-520825-19-00)
  • 06 May 2025 Takeda plans a phase III trial for Idiopathic thrombocytopenic purpura (SC), in August 2025 (NCT06948318) (EUCT2025-521692-31-00)

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