Mezagitamab - Takeda
Alternative Names: Anti-CD38 mAb; TAK-079Latest Information Update: 14 May 2025
At a glance
- Originator Takeda
- Class Antineoplastics; Antirheumatics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Idiopathic thrombocytopenic purpura
- Phase II Multiple myeloma; Myasthenia gravis
- Phase I/II Systemic lupus erythematosus
- Phase I IgA nephropathy
- Discontinued Rheumatoid arthritis
Most Recent Events
- 09 May 2025 Takeda plans a phase III trial for IgA nephropathy (Combination therapy, Treatment-experienced) (SC, Injection) in August 2025 (NCT06963827) (EUCT2025-520825-19-00)
- 06 May 2025 Takeda plans a phase III trial for Idiopathic thrombocytopenic purpura (SC), in August 2025 (NCT06948318) (EUCT2025-521692-31-00)
- 27 Feb 2025 Phase-III clinical trials in Idiopathic thrombocytopenic purpura (Treatment-experienced) in China, Japan (SC) (NCT06722235) (EudraCT2024-514401-54-00)