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At a glance
Originator
Takeda
Class
Antineoplastics; Antirheumatics; Immunotherapies; Monoclonal antibodies
Mechanism of Action
Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
Yes
-
Multiple myeloma
New Molecular Entity
Yes
Highest Development Phases
Phase II
Idiopathic thrombocytopenic purpura; Multiple myeloma; Myasthenia gravis
Phase I
Systemic lupus erythematosus
Discontinued
Rheumatoid arthritis
Most Recent Events
13 Apr 2021
Takeda anticipates the approval of mezagitamab for Idiopathic thrombocytopenic purpura and Myasthenia gravis in 2025/2026 (Takeda pipeline, April 2021)
06 Dec 2020
Updated pharmacokinetics data from a phase I/II trial in Multiple myeloma presented at the 62nd American Society of Haematology Annual Meeting (ASH-2020)
31 Aug 2020
Phase-II clinical trials in Idiopathic thrombocytopenic purpura in USA (SC) (NCT04278924)
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