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Zorifertinib - AstraZeneca

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Drug Profile

Zorifertinib - AstraZeneca

Alternative Names: AZD-3759; Zorifer; Zorifertinib hydrochloride - AstraZeneca

Latest Information Update: 08 Sep 2025

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At a glance

  • Originator AstraZeneca
  • Developer Alpha Biopharma; AstraZeneca
  • Class Amines; Antineoplastics; Piperazines; Quinazolines; Small molecules
  • Mechanism of Action Epidermal growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Cancer metastases; Non-small cell lung cancer

Most Recent Events

  • 08 Sep 2025 Alpha Biopharma plans a observational trial for Non small cell lung cancer (Late stage disease, First line therapy) in October 2025 (NCT07143045)
  • 22 Nov 2024 Phase-II clinical trials in Cancer metastases (Combination therapy, Second-line therapy or greater) (PO), before November 2024 (Alpha Biopharma pipeline, November 2024)
  • 22 Nov 2024 Phase-II clinical trials in Cancer metastases (Second-line therapy or greater) (PO), before November 2024 (Alpha Biopharma pipeline, November 2024)

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