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CB 5083

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Drug Profile

CB 5083

Alternative Names: CB-5083

Latest Information Update: 21 Jul 2021

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At a glance

  • Originator Cleave Biosciences
  • Developer Cleave Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action CDC48 inhibitors; P97 ATPase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Multiple myeloma; Solid tumours

Most Recent Events

  • 17 Apr 2021 Pharmacodynamics data from a preclinical trial in Multiple myeloma presented at the 73rd Annual Meeting of the American Academy of Neurology (AAN-2021)
  • 28 Mar 2020 No recent reports of development identified for phase-I development in Multiple-myeloma(Second-line therapy or greater) in USA (PO)
  • 28 Mar 2020 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO)

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