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NLX 101

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Drug Profile

NLX 101

Alternative Names: F15599; NLX-101

Latest Information Update: 05 Feb 2025

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At a glance

  • Originator Pierre Fabre
  • Developer Neurolixis
  • Class Antidementias; Antidepressants; Antipsychotics; Piperidines; Pyrimidines; Small molecules
  • Mechanism of Action 5-HT1A serotonin receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Rett syndrome; Fragile X syndrome
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Fragile X syndrome
  • No development reported Depressive disorders; Rett syndrome
  • Discontinued Cognition disorders; Mood disorders; Schizophrenia

Most Recent Events

  • 24 Jan 2025 NLX 101 receives Orphan Drug status for Fragile X syndrome
  • 28 Sep 2024 No recent reports of development identified for phase-I development in Rett syndrome(In volunteers) in USA (PO)
  • 28 Sep 2024 No recent reports of development identified for preclinical development in Depressive disorders in USA

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