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Axitinib ophthalmic - Clearside Biomedical

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Drug Profile

Axitinib ophthalmic - Clearside Biomedical

Alternative Names: Axitinib injectable suspension - Clearside Biomedical; CLS 1002; CLS-AX; CLS011A

Latest Information Update: 14 Mar 2025

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At a glance

  • Originator Clearside Biomedical
  • Class Antineoplastics; Benzamides; Eye disorder therapies; Imidazoles; Indazoles; Pyridines; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Platelet-derived growth factor beta receptor antagonists; Protein tyrosine kinase inhibitors; Proto-oncogene protein c-kit inhibitors; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists; Vascular endothelial growth factor receptor-3 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Wet age-related macular degeneration

Most Recent Events

  • 06 Mar 2025 Clearside Biomedical complets an End-of-Phase II meeting with the US FDA for Wet age-related macular degeneration (AMD)
  • 12 Nov 2024 Clearside Biomedical plans an end-of-phase II meeting with the US FDA for phase III trial for Wet age-related macular degeneration in early 2025
  • 09 Oct 2024 Efficacy and adverse events data from phase-IIb ODYSSEY trial in Wet age related macular degeneration released by Clearside Biomedical

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