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Research programme: TAM receptor tyrosine kinase targeting therapeutics - Celldex Therapeutics Inc

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Drug Profile

Research programme: TAM receptor tyrosine kinase targeting therapeutics - Celldex Therapeutics Inc

Alternative Names: TAM RTK - Celldex Therapeutics; Tyro3/Axl/MerTK program - Celldex Therapeutics

Latest Information Update: 28 May 2023

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At a glance

  • Originator Salk Institute
  • Developer Celldex Therapeutics Inc; Salk Institute
  • Class Monoclonal antibodies
  • Mechanism of Action Axl receptor tyrosine kinase modulators; Receptor protein-tyrosine kinase modulators; TYRO3 receptor protein tyrosine kinase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Autoimmune disorders; Cancer; Infections

Most Recent Events

  • 28 May 2023 No recent reports of development identified for preclinical development in Cancer in USA
  • 02 Apr 2019 Preclinical trials in Cancer in USA (unspecified route)
  • 02 Apr 2019 Pharmacodynamics data from a preclinical study in Cancer released by Celldex Therapeutics

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