Drug Profile


Alternative Names: CM 4307

Latest Information Update: 01 Nov 2017

Price : *
* Final gross price and currency may vary according to local VAT and billing address.
* Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase. A link to download a PDF version of the drug profile will be included in your email receipt. Adis is an information provider. We do not sell or distribute the pharmaceutical compounds written about in this database.

At a glance

  • Originator Suzhou Zelgen Biopharmaceuticals
  • Class Antineoplastics
  • Mechanism of Action Raf kinase inhibitors; Receptor protein-tyrosine kinase antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Colorectal cancer
  • Phase II/III Hepatocellular carcinoma
  • Phase II Thyroid cancer
  • Phase I/II Gastric cancer; Oesophageal cancer
  • Phase I Nasopharyngeal cancer

Most Recent Events

  • 01 Dec 2016 Phase-III clinical trials in Colorectal cancer (Metastatic disease, Second-line therapy or greater) in China (PO) (NCT02870582)
  • 01 Sep 2016 Phase-II clinical trials in Thyroid cancer in China (PO) (NCT02870569)
  • 12 Aug 2016 Suzhou Zelgen Biopharmaceuticals plans a phase II trial in Thyroid cancer in China (NCT02870569)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at so we can help.

Back to top