Donafenib - Suzhou Zelgen Biopharmaceuticals

Drug Profile

Donafenib - Suzhou Zelgen Biopharmaceuticals

Alternative Names: CM 4307

Latest Information Update: 14 Aug 2018

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At a glance

  • Originator Suzhou Zelgen Biopharmaceuticals
  • Class Amides; Antineoplastics; Benzenesulfonates; Chlorobenzenes; Pyridines; Small molecules
  • Mechanism of Action Raf kinase inhibitors; Receptor protein-tyrosine kinase antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Colorectal cancer; Thyroid cancer
  • Phase II/III Hepatocellular carcinoma
  • Phase I/II Gastric cancer; Oesophageal cancer
  • Phase I Nasopharyngeal cancer

Most Recent Events

  • 14 Aug 2018 Chemical structure information added
  • 04 Jul 2018 Suzhou Zelgen Biopharmaceuticals initiates enrolment in a Bioequvalence trial for Healthy volunteers in China (ChiCTR1800017112)
  • 26 Jun 2018 Phase-III clinical trials in Thyroid cancer (Late-stage disease) in China (PO) (NCT03602495)
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