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Trilaciclib - G1 Therapeutics

Drug Profile

Trilaciclib - G1 Therapeutics

Alternative Names: COSELA; G1T 28; G1T28-1

Latest Information Update: 27 Jun 2024

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At a glance

  • Originator G1 Therapeutics
  • Developer Boehringer Ingelheim; G1 Therapeutics; Quantum Leap Healthcare Collaborative; Simcere Pharmaceutical Group
  • Class Amines; Antineoplastics; Aza compounds; Chemoprotectants; Cyclohexanes; Ketones; Piperazines; Pyrazines; Pyridines; Pyrimidines; Pyrroles; Radioprotectives; Small molecules; Spiro compounds
  • Mechanism of Action Cyclin-dependent kinase 4 inhibitors; Cyclin-dependent kinase 6 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Myelosuppression; Small cell lung cancer
  • Phase III Colorectal cancer; Triple negative breast cancer
  • Phase II Bladder cancer; Breast cancer; Non-small cell lung cancer
  • No development reported Cancer

Most Recent Events

  • 24 Jun 2024 Trilaciclib - G1 Therapeutics is available for licensing as of 24 Jun 2024. https://www.g1therapeutics.com/
  • 24 Jun 2024 Efficacy and adverse events data from the phase III PRESERVE 2 trial in Triple negative breast cancer released by G1 Therapeutics
  • 31 May 2024 Updated efficacy and adverse events data from a phase II trial in Triple-negative-breast-cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
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