Folate fluorescein isothiocyanate conjugate - On Target Laboratories

Drug Profile

Folate fluorescein isothiocyanate conjugate - On Target Laboratories

Alternative Names: EC-17; Folate receptor-alpha-targeted fluorescent agent - OnTarget Laboratories; Folate receptor-alpha-targeted imaging agent - OnTarget Laboratories; Folate-5-fluorescein isothiocyanate; Folate-FITC conjugate; Folate-fluorescein isothiocyanate; OTL-0038; OTL-38

Latest Information Update: 07 Feb 2018

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At a glance

  • Originator Endocyte; Purdue University
  • Developer Centre for Human Drug Research; Indiana University School of Medicine; Leiden University Medical Center; On Target Laboratories; Purdue University; University of Pennsylvania
  • Class Cancer vaccines; Fluoresceins; Haptens; Imaging agents
  • Mechanism of Action Diagnostic imaging enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Ovarian cancer
  • Phase II Lung cancer
  • Phase I Breast cancer; Pituitary cancer; Primary hyperparathyroidism; Renal cell carcinoma

Most Recent Events

  • 26 Jan 2018 Phase-III clinical trials in Ovarian cancer (Diagnosis) in USA (IV) (NCT03180307)
  • 12 Jun 2017 On Target Laboratories plans a phase III trial for Ovarian cancer (Diagnosis) (NCT03180307)
  • 04 May 2017 Phase-II clinical trials in Lung cancer (Diagnosis) in USA (IV) (NCT02872701)
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