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Cannabidiol - Zynerba Pharmaceuticals

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Drug Profile

Cannabidiol - Zynerba Pharmaceuticals

Alternative Names: Cannabidiol gel patch; Cannabidiol transdermal gel; CBD; CBD gel patch; CBD transdermal gel; Synthetic CBD; Topical cannabidiol gel; Topical CBD gel; Transdermal CBD gel; Zygel; ZYN-002

Latest Information Update: 21 Jan 2026

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At a glance

  • Originator Zynerba Pharmaceuticals
  • Class Analgesics; Anti-inflammatories; Anti-ischaemics; Antiacnes; Antibacterials; Antiepileptic drugs; Antihyperglycaemics; Antihyperlipidaemics; Antineoplastics; Antiparkinsonians; Antipsoriatics; Antipsychotics; Antirheumatics; Anxiolytics; Behavioural disorder therapies; Cannabinoids; Cardiovascular therapies; Cyclohexenes; Drug withdrawal therapies; Heart failure therapies; Hepatoprotectants; Muscle relaxants; Neuroprotectants; Obesity therapies; Resorcinols; Skin disorder therapies; Small molecules
  • Mechanism of Action 5-HT1 serotonin receptor modulators; Antioxidants; Cannabinoid receptor CB1 inverse agonists; Cannabinoid receptor CB2 inverse agonists; Transient receptor potential channel modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Fragile X syndrome; DiGeorge syndrome
  • New Molecular Entity No

Highest Development Phases

  • Phase II Autism spectrum disorder; Epilepsy
  • No development reported Alcoholism; Rheumatoid arthritis; Substance-related disorders
  • Discontinued DiGeorge syndrome; Fragile X syndrome; Osteoarthritis

Most Recent Events

  • 21 Jan 2026 Discontinued - Phase-II for DiGeorge syndrome (In adolescents, In children) in Australia (Transdermal)
  • 21 Jan 2026 Discontinued - Phase-II for DiGeorge syndrome (In adolescents, In children) in USA (Transdermal)
  • 13 Jan 2026 Discontinued - Phase-II/III for Fragile X syndrome (In adolescents, In children) in New Zealand (Transdermal)

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