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Efmitermant alfa - Acceleron Pharma

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Drug Profile

Efmitermant alfa - Acceleron Pharma

Alternative Names: ACE-083

Latest Information Update: 01 Dec 2021

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At a glance

  • Originator Acceleron Pharma
  • Class Neuroprotectants; Recombinant fusion proteins
  • Mechanism of Action TGF-beta superfamily protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Charcot-Marie-Tooth disease; Facioscapulohumeral muscular dystrophy
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Charcot-Marie-Tooth disease; Facioscapulohumeral muscular dystrophy; Inclusion body myositis

Most Recent Events

  • 22 Nov 2021 Acceleron Pharma has been acquired by Merck & Co
  • 13 Mar 2020 Acceleron Pharma terminates a phase II trial in Charcot-Marie-Tooth disease in USA due to failure of the trial to meet primary and secondary endpoints (NCT03124459)
  • 10 Mar 2020 Discontinued - Phase-II for Charcot-Marie-Tooth disease in USA, Canada, Spain (IM)

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