Metablok - Arch Biopartners
Alternative Names: LSALT peptide; MetaBlokLatest Information Update: 29 Apr 2025
At a glance
- Originator Arch Biopartners; University of Calgary
- Developer Arch Biopartners; Sunnybrook Health Sciences Centre; University of Calgary
- Class Peptides; Small molecules
- Mechanism of Action Dipeptidase inhibitors
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Acute kidney injury; COVID 2019 infections; SARS-CoV-2 acute respiratory disease
- No development reported Cancer metastases; Sepsis
Most Recent Events
- 22 Apr 2025 University Health Network (UHN) Research Ethics Board approves Toronto General Hospital to participate in the CS-AKI Phase II trial
- 15 Jan 2025 9433517: Updated KDM and added HE for the same (update discussed with SME (Akash)
- 08 Jan 2025 University Health Network Research Ethics Board through the Clinical Trials Ontario Streamlined Research Ethics Review System grants provincial ethics approval for the Phase II trial for Metablok in Acute kidney injury