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Metablok - Arch Biopartners

Drug Profile

Metablok - Arch Biopartners

Alternative Names: LSALT peptide; MetaBlok

Latest Information Update: 29 Apr 2025

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At a glance

  • Originator Arch Biopartners; University of Calgary
  • Developer Arch Biopartners; Sunnybrook Health Sciences Centre; University of Calgary
  • Class Peptides; Small molecules
  • Mechanism of Action Dipeptidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute kidney injury; COVID 2019 infections; SARS-CoV-2 acute respiratory disease
  • No development reported Cancer metastases; Sepsis

Most Recent Events

  • 22 Apr 2025 University Health Network (UHN) Research Ethics Board approves Toronto General Hospital to participate in the CS-AKI Phase II trial
  • 15 Jan 2025 9433517: Updated KDM and added HE for the same (update discussed with SME (Akash)
  • 08 Jan 2025 University Health Network Research Ethics Board through the Clinical Trials Ontario Streamlined Research Ethics Review System grants provincial ethics approval for the Phase II trial for Metablok in Acute kidney injury

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