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PBF 999

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Drug Profile

PBF 999

Alternative Names: PBF-999

Latest Information Update: 17 Jul 2023

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At a glance

  • Originator Palobiofarma
  • Developer Fundacio Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau; Palobiofarma
  • Class Antineoplastics; Antipsychotics; Obesity therapies
  • Mechanism of Action Adenosine A2A receptor antagonists; Phosphodiesterase 10A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Huntington's disease
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Prader-Willi syndrome
  • Discontinued Cancer; Huntington's disease

Most Recent Events

  • 17 Jul 2023 Discontinued - Phase-I for Cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in Spain (unspecified route) (Palobiofarma pipeline, July 2023)
  • 17 Jul 2023 Phase-II clinical trials in Prader-Willi syndrome (unspecified route) before July 2023 (Palobiofarma pipeline, July 2023)
  • 06 Jan 2022 Development for Cancer is underway in Spain (Palobiofarma pipeline, January 2022)

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